Icy

Icy is an image analysis software primarily targeted at biological needs. It provides high-quality tools for biological image processing tasks, such as filtering (linear, nonlinear, morphological, etc.), cell segmentation, particles detection, tracking, multiple-class thresholding, measurements, microscope control, etc. It is designed to work on sequences from 2D to 5D (X, Y, Z, time, color channel), and runs on Windows, MacOS, Linux.
Find Icy at: http://icy.bioimageanalysis.org/